PDZ Interaction Sites in Integrin α Subunits
نویسندگان
چکیده
منابع مشابه
PDZ Domain-mediated interaction of interleukin-16 precursor proteins with myosin phosphatase targeting subunits.
The cytokine interleukin-16 is generated by posttranscriptional cleavage by caspase-3 of two large precursor isoforms. The smaller protein of 67 kDa (pro-IL-16) is expressed in cells of the immune system and contains three PDZ (postsynaptic density/disc large/zona occludens-1) domains, whereas the larger 141-kDa neuronal variant (npro-IL-16) has two additional PDZ domains in its N-terminal exte...
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Asymmetric Interaction between Rod Cyclic GMP Phosphodiesterase Subunits and Subunits*
Rod phosphodiesterase (PDE6) is the central effector enzyme in vertebrate visual transduction. Holo-PDE6 consists of two similar catalytic subunits (P ) and two identical inhibitory subunits (P ). P is the only heterodimer in the PDE superfamily, yet its significance for the function of PDE6 is poorly understood. An unequal interaction of P with P as compared with P in the PDE6 complex has not ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2001
ISSN: 0021-9258
DOI: 10.1074/jbc.m105785200